Prokinetics for functional dyspepsia

Prokinetics for the treatment of functional dyspepsia: Bayesian network meta-analysis

BACKGROUND Controversies persist regarding the effect of prokinetics for the treatment of functional dyspepsia (FD). This study aimed to assess the comparative efficacy of prokinetic agents for the treatment of FD. METHODS Randomized controlled trials (RCTs) of prokinetics for the treatment of FD were identified from core databases. Symptom response rates were extracted and analyzed using odd...

Functional Dyspepsia

Dyspepsia is a common clinical condition associated with a complex of upper abdominal symptoms including: upper centered discomfort or pain, feeling of abdominal fullness, early satiety, abdominal distention and bloating, belching, and nausea. The exact prevalence of dyspepsia in the general population is not known, but it is estimated that as many as 25% to 40% of adults experience symptoms of...

Diagnostic Testing for Functional Dyspepsia

Overlap in Patients With Dyspepsia/Functional Dyspepsia

Patients with dyspepsia/functional dyspepsia (FD) show frequent overlapping of other gastrointestinal (GI) diseases, such as irri-table bowel syndrome, and non-GI diseases, in addition to internal subgroup overlapping. These overlap patients have more frequent or more severe symptoms, poorer health-related quality of life and higher somatization scores, and they are more like-ly to experience a...

Is Functional Dyspepsia Idiopathic?

Dyspepsia is currently defined by Rome III criteria for the diagnosis of functional gastroin‐ testinal disorders (FGIDs), as the presence of one or more of the following symptoms: both‐ ersome postprandial fullness, early satiation, epigastric pain and epigastric burning [1] These are symptoms thought to originate from the gastroduodenal region. Bloating and nausea often coexist with dyspepsia ...